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This has been a tough battle, but it is a critically important and necessary one

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Circulating monocytes which migrate to the lung are differentiated uncommitted macrophages (M0), and they are broadly polarized to pro-inflammatory M1 macrophages and anti-inflammatory M2 macrophages that highly express HO-1 35,36,37

We need to move away from binary decisions about medication access toward an individualized approach to treatment selection and support.